Genetic variability of 15 autosomal STR loci in Russian populations

Genetic variability of 15 autosomal STR loci in Russian populations

Abstract Allele frequencies for 15 STRs (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, THO1, TPOX, and vWA) in the PowerPlex 16 System (Promega Corporation) were assessed in 386 individuals from five Russian urban populations. No significant betwe...

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Veröffentlicht in:Legal medicine (Tokyo, Japan) Japan), 2010-09, Vol.12 (5), p.256-258
Hauptverfasser: Stepanov, Vadim A, Melnikov, Alexander V, Lash-Zavada, Andrey Yu, Kharkov, Vladimir N, Borinskaya, Svetlana A, Tyazhelova, Tatiana V, Zhukova, Olga V, Schneider, Yuri V, Shil’nikova, Irina N, Puzyrev, Valery P, Rybakova, Anna A, Yankovsky, Nikolai K
Format: Artikel
Sprache:eng
Schlagworte:
Alleles
European Continental Ancestry Group - genetics
Forensic Genetics
Gene Frequency
Genetic Variation
Genetics, Population
Humans
Internal Medicine
Polymerase Chain Reaction
Polymorphism, Genetic
Population data
PowerPlex® 16 System
Russia
Russian population
Short tandem repeats (STR)
Tandem Repeat Sequences - genetics
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Zusammenfassung:Abstract Allele frequencies for 15 STRs (CSF1PO, D3S1358, D5S818, D7S820, D8S1179, D13S317, D16S539, D18S51, D21S11, FGA, Penta D, Penta E, THO1, TPOX, and vWA) in the PowerPlex 16 System (Promega Corporation) were assessed in 386 individuals from five Russian urban populations. No significant between-population differences in frequencies and molecular variance of 15 microsatellites were revealed. For all 15 loci, the combined matching probability is 3.19 × 10−18 and the power of exclusion is 99.99989%.
ISSN:1344-6223
1873-4162
DOI:10.1016/j.legalmed.2010.05.006