Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling

Rate-dependent action potential alternans in human heart failure implicates abnormal intracellular calcium handling

Background Alternans in action potential voltage (APV-ALT) at heart rates 400% for CL 500% at CL

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Bibliographische Detailangaben
Veröffentlicht in:Heart rhythm 2010-08, Vol.7 (8), p.1093-1101
Hauptverfasser: Bayer, Jason D., MS, Narayan, Sanjiv M., MD, FHRS, Lalani, Gautam G., MD, Trayanova, Natalia A., PhD, FHRS, FAHA
Format: Artikel
Sprache:eng
Schlagworte:
Action potential alternans
Action Potentials - physiology
Aged
Arrhythmias, Cardiac - etiology
Arrhythmias, Cardiac - physiopathology
Calcium - metabolism
Calcium handling
Calcium Metabolism Disorders - complications
Calcium Metabolism Disorders - physiopathology
Cardiac Pacing, Artificial
Cardiovascular
Computer modeling
Heart failure
Heart Failure - complications
Heart Failure - physiopathology
Heart Rate - physiology
Humans
Middle Aged
Models, Cardiovascular
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Beschreibung
Zusammenfassung:Background Alternans in action potential voltage (APV-ALT) at heart rates 400% for CL 500% at CL
ISSN:1547-5271
1556-3871
DOI:10.1016/j.hrthm.2010.04.008