Brugada sign unmasking the location of an acute myocardial infarction

Two patients with acute myocardial infarction were admitted with unremarkable electrocardiograms, which did not reveal the location of the damage. A review of these electrocardiograms led to a suspicion of the presence of Brugada sign (BRSG), something subsequently confirmed by the administration of a sodium channel blocker. The unmasking of BRSG was unexpectedly accompanied by repolarisation abnormalities, showing ischaemia in the lateral wall, concordant with the distribution of the culprit vessels in the coronary angiogram.