Medical Management of Refractory Status Epilepticus

This review discusses the medical management of pediatric refractory status epilepticus, defined here as persistent seizures of any type after the administration of 2 appropriate anticonvulsants. The use of both nonanesthetic and anesthetic anticonvulsants is discussed along with the relative streng...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Seminars in pediatric neurology 2010-09, Vol.17 (3), p.176-181
1. Verfasser: Owens, James, MD, PhD
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 181
container_issue 3
container_start_page 176
container_title Seminars in pediatric neurology
container_volume 17
creator Owens, James, MD, PhD
description This review discusses the medical management of pediatric refractory status epilepticus, defined here as persistent seizures of any type after the administration of 2 appropriate anticonvulsants. The use of both nonanesthetic and anesthetic anticonvulsants is discussed along with the relative strengths and weaknesses of each agent. Appropriate treatment goals and the use of electroencephalographic monitoring are described as are reasonable treatment algorithms. Finally, ethical considerations are briefly discussed in the context of available outcome data.
doi_str_mv 10.1016/j.spen.2010.06.006
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_749012067</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>1_s2_0_S1071909110000653</els_id><sourcerecordid>749012067</sourcerecordid><originalsourceid>FETCH-LOGICAL-c410t-bd077fd94bef64ccc7820ceed7c6f3fe6363905fd8838bb852a52cb81d8001ea3</originalsourceid><addsrcrecordid>eNp9kUtLxTAQhYMovv-AC-nOVa-TpE1yQQQRX6AIPtYhTSeSa29bk1a4_96Uqy5cmM0kwzmHzDeEHFGYUaDidDGLPbYzBqkBYgYgNsguLUuVg5RiM91B0nwOc7pD9mJcAPAivbbJDgPJZKHkLuEPWHtrmuzBtOYNl9gOWeeyJ3TB2KELq-x5MMMYs6veN9gP3o7xgGw500Q8_K775PX66uXyNr9_vLm7vLjPbUFhyKs6fcPV86JCJwprrVQMLGItrXDcoeCCz6F0tVJcVZUqmSmZrRStFQBFw_fJyTq3D93HiHHQSx8tNo1psRujlmkaykDIpGRrpQ1djAGd7oNfmrDSFPTESi_0xEpPrDQInVgl0_F3_Fgtsf61_MBJgrO1ANOQnx6DjtZjaxOxgHbQdef_zz__Y7eNbyfY77jCuOjG0CZ8murINOjnaVvTsiikI0rOvwD3Uo84</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>749012067</pqid></control><display><type>article</type><title>Medical Management of Refractory Status Epilepticus</title><source>MEDLINE</source><source>Elsevier ScienceDirect Journals</source><creator>Owens, James, MD, PhD</creator><creatorcontrib>Owens, James, MD, PhD</creatorcontrib><description>This review discusses the medical management of pediatric refractory status epilepticus, defined here as persistent seizures of any type after the administration of 2 appropriate anticonvulsants. The use of both nonanesthetic and anesthetic anticonvulsants is discussed along with the relative strengths and weaknesses of each agent. Appropriate treatment goals and the use of electroencephalographic monitoring are described as are reasonable treatment algorithms. Finally, ethical considerations are briefly discussed in the context of available outcome data.</description><identifier>ISSN: 1071-9091</identifier><identifier>EISSN: 1558-0776</identifier><identifier>DOI: 10.1016/j.spen.2010.06.006</identifier><identifier>PMID: 20727487</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Anticonvulsants - administration &amp; dosage ; Child ; Clinical Protocols ; Drug Resistance ; Humans ; Infusions, Intravenous ; Neurology ; Pediatrics ; Status Epilepticus - diagnosis ; Status Epilepticus - drug therapy</subject><ispartof>Seminars in pediatric neurology, 2010-09, Vol.17 (3), p.176-181</ispartof><rights>Elsevier Inc.</rights><rights>2010 Elsevier Inc.</rights><rights>Copyright 2010 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c410t-bd077fd94bef64ccc7820ceed7c6f3fe6363905fd8838bb852a52cb81d8001ea3</citedby><cites>FETCH-LOGICAL-c410t-bd077fd94bef64ccc7820ceed7c6f3fe6363905fd8838bb852a52cb81d8001ea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/j.spen.2010.06.006$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,777,781,3537,27905,27906,45976</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20727487$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Owens, James, MD, PhD</creatorcontrib><title>Medical Management of Refractory Status Epilepticus</title><title>Seminars in pediatric neurology</title><addtitle>Semin Pediatr Neurol</addtitle><description>This review discusses the medical management of pediatric refractory status epilepticus, defined here as persistent seizures of any type after the administration of 2 appropriate anticonvulsants. The use of both nonanesthetic and anesthetic anticonvulsants is discussed along with the relative strengths and weaknesses of each agent. Appropriate treatment goals and the use of electroencephalographic monitoring are described as are reasonable treatment algorithms. Finally, ethical considerations are briefly discussed in the context of available outcome data.</description><subject>Anticonvulsants - administration &amp; dosage</subject><subject>Child</subject><subject>Clinical Protocols</subject><subject>Drug Resistance</subject><subject>Humans</subject><subject>Infusions, Intravenous</subject><subject>Neurology</subject><subject>Pediatrics</subject><subject>Status Epilepticus - diagnosis</subject><subject>Status Epilepticus - drug therapy</subject><issn>1071-9091</issn><issn>1558-0776</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kUtLxTAQhYMovv-AC-nOVa-TpE1yQQQRX6AIPtYhTSeSa29bk1a4_96Uqy5cmM0kwzmHzDeEHFGYUaDidDGLPbYzBqkBYgYgNsguLUuVg5RiM91B0nwOc7pD9mJcAPAivbbJDgPJZKHkLuEPWHtrmuzBtOYNl9gOWeeyJ3TB2KELq-x5MMMYs6veN9gP3o7xgGw500Q8_K775PX66uXyNr9_vLm7vLjPbUFhyKs6fcPV86JCJwprrVQMLGItrXDcoeCCz6F0tVJcVZUqmSmZrRStFQBFw_fJyTq3D93HiHHQSx8tNo1psRujlmkaykDIpGRrpQ1djAGd7oNfmrDSFPTESi_0xEpPrDQInVgl0_F3_Fgtsf61_MBJgrO1ANOQnx6DjtZjaxOxgHbQdef_zz__Y7eNbyfY77jCuOjG0CZ8murINOjnaVvTsiikI0rOvwD3Uo84</recordid><startdate>20100901</startdate><enddate>20100901</enddate><creator>Owens, James, MD, PhD</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20100901</creationdate><title>Medical Management of Refractory Status Epilepticus</title><author>Owens, James, MD, PhD</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c410t-bd077fd94bef64ccc7820ceed7c6f3fe6363905fd8838bb852a52cb81d8001ea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>Anticonvulsants - administration &amp; dosage</topic><topic>Child</topic><topic>Clinical Protocols</topic><topic>Drug Resistance</topic><topic>Humans</topic><topic>Infusions, Intravenous</topic><topic>Neurology</topic><topic>Pediatrics</topic><topic>Status Epilepticus - diagnosis</topic><topic>Status Epilepticus - drug therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Owens, James, MD, PhD</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Seminars in pediatric neurology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Owens, James, MD, PhD</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Medical Management of Refractory Status Epilepticus</atitle><jtitle>Seminars in pediatric neurology</jtitle><addtitle>Semin Pediatr Neurol</addtitle><date>2010-09-01</date><risdate>2010</risdate><volume>17</volume><issue>3</issue><spage>176</spage><epage>181</epage><pages>176-181</pages><issn>1071-9091</issn><eissn>1558-0776</eissn><abstract>This review discusses the medical management of pediatric refractory status epilepticus, defined here as persistent seizures of any type after the administration of 2 appropriate anticonvulsants. The use of both nonanesthetic and anesthetic anticonvulsants is discussed along with the relative strengths and weaknesses of each agent. Appropriate treatment goals and the use of electroencephalographic monitoring are described as are reasonable treatment algorithms. Finally, ethical considerations are briefly discussed in the context of available outcome data.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>20727487</pmid><doi>10.1016/j.spen.2010.06.006</doi><tpages>6</tpages></addata></record>
fulltext fulltext
identifier ISSN: 1071-9091
ispartof Seminars in pediatric neurology, 2010-09, Vol.17 (3), p.176-181
issn 1071-9091
1558-0776
language eng
recordid cdi_proquest_miscellaneous_749012067
source MEDLINE; Elsevier ScienceDirect Journals
subjects Anticonvulsants - administration & dosage
Child
Clinical Protocols
Drug Resistance
Humans
Infusions, Intravenous
Neurology
Pediatrics
Status Epilepticus - diagnosis
Status Epilepticus - drug therapy
title Medical Management of Refractory Status Epilepticus
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T16%3A40%3A42IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Medical%20Management%20of%20Refractory%20Status%20Epilepticus&rft.jtitle=Seminars%20in%20pediatric%20neurology&rft.au=Owens,%20James,%20MD,%20PhD&rft.date=2010-09-01&rft.volume=17&rft.issue=3&rft.spage=176&rft.epage=181&rft.pages=176-181&rft.issn=1071-9091&rft.eissn=1558-0776&rft_id=info:doi/10.1016/j.spen.2010.06.006&rft_dat=%3Cproquest_cross%3E749012067%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=749012067&rft_id=info:pmid/20727487&rft_els_id=1_s2_0_S1071909110000653&rfr_iscdi=true