The Application of Organic Electrochemical Transistors in Cell-Based Biosensors

Cells are cultivated on top of an organic electrochemical transistor. The activities of the cells can be monitored by characterizing the transistor because the performance of the transistor is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interacti...

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Veröffentlicht in:	Advanced materials (Weinheim) 2010-09, Vol.22 (33), p.3655-3660
Hauptverfasser:	Lin, Peng, Yan, Feng, Yu, Jinjiang, Chan, Helen L. W., Yang, Mo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic Agents - pharmacology Biosensing Techniques - instrumentation Biosensors Bridged Bicyclo Compounds, Heterocyclic - chemistry cancer cell Cell Line Cell Line, Tumor cell-based biosensor Electrochemistry - instrumentation Equipment Design Fibroblasts - cytology Fibroblasts - metabolism Fibroblasts - ultrastructure Humans Morphology Organic electrochemcial transistor PEDOT Polymers - chemistry Polystyrenes - chemistry Semiconductor devices Surface charge Transistors Tretinoin - pharmacology Trypsin - metabolism
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Beschreibung
Zusammenfassung:	Cells are cultivated on top of an organic electrochemical transistor. The activities of the cells can be monitored by characterizing the transistor because the performance of the transistor is sensitive to the surface charge and the morphology of the attached cells due to the electrostatic interaction between the cells and the active layer of the transistor.
ISSN:	0935-9648 1521-4095
DOI:	10.1002/adma.201000971