Angiotensin-Forming Enzyme in Brain Tissue

A renin-like enzyme is present in brain tissue and is independent of kidney and plasma renin. In the presence of homologous substrate it forms angiotensin. Administration of aldosterone significantly decreases this angiotensin-forming enzyme activity, while administration of progesterone markedly en...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Science (American Association for the Advancement of Science) 1971-07, Vol.173 (3991), p.64-65
Hauptverfasser:	Ganten, Detlev, Minnich, James L., Granger, Pierre, Hayduk, Karl, Brecht, Hans Michael, Barbeau, André, Boucher, Roger, Genest, Jacques
Format:	Artikel
Sprache:	eng
Schlagworte:	Aldosterone - pharmacology Angiotensin II - biosynthesis Animals Blood plasma Brain Brain Chemistry Caudate nucleus Caudate Nucleus - analysis Caudate Nucleus - drug effects Caudate Nucleus - enzymology Depression, Chemical Dogs Enzyme activity Enzyme substrates Enzymes Kidneys Neurons Progesterone - pharmacology Renin - analysis Sodium Sodium - metabolism Stimulation, Chemical
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A renin-like enzyme is present in brain tissue and is independent of kidney and plasma renin. In the presence of homologous substrate it forms angiotensin. Administration of aldosterone significantly decreases this angiotensin-forming enzyme activity, while administration of progesterone markedly enhances it.
ISSN:	0036-8075 1095-9203
DOI:	10.1126/science.173.3991.64