Asymmetric DNA Origami for Spatially Addressable and Index-Free Solution-Phase DNA Chips

Asymmetric DNA Origami for Spatially Addressable and Index-Free Solution-Phase DNA Chips

A solution‐phase DNA chip is produced using DNA origami‐based asymmetric self‐assembled tiles incorporating single‐stranded DNA linear probes. This DNA origami chip is fully spatially addressable, without having to use position index oligonucleotides. The DNA hybridization is readily detected via at...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Advanced materials (Weinheim) 2010-06, Vol.22 (24), p.2672-2675
Hauptverfasser: Zhang, Zhao, Wang, Ying, Fan, Chunhai, Li, Can, Li, You, Qian, Lulu, Fu, Yanming, Shi, Yongyong, Hu, Jun, He, Lin
Format: Artikel
Sprache:eng
Schlagworte:
DNA
DNA - chemistry
DNA - metabolism
Microscopy, Atomic Force
Nanoscale
Nanotechnology - instrumentation
Solutions
Streptavidin - metabolism
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A solution‐phase DNA chip is produced using DNA origami‐based asymmetric self‐assembled tiles incorporating single‐stranded DNA linear probes. This DNA origami chip is fully spatially addressable, without having to use position index oligonucleotides. The DNA hybridization is readily detected via atomic force microscopy.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201000151