Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander

Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Chemical & Pharmaceutical Bulletin 2010/08/01, Vol.58(8), pp.1088-1092
Hauptverfasser: Bai, Liming, Zhao, Ming, Toki, Asami, Sakai, Jun-ichi, Yang, Xiao-yang, Bai, Yuhua, Ando, Mariko, Hirose, Katsutoshi, Ando, Masayoshi
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 1092
container_issue 8
container_start_page 1088
container_title Chemical & Pharmaceutical Bulletin
container_volume 58
creator Bai, Liming
Zhao, Ming
Toki, Asami
Sakai, Jun-ichi
Yang, Xiao-yang
Bai, Yuhua
Ando, Mariko
Hirose, Katsutoshi
Ando, Masayoshi
description Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.
doi_str_mv 10.1248/cpb.58.1088
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_748949705</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>3133733851</sourcerecordid><originalsourceid>FETCH-LOGICAL-c667t-8c64265558ce1b4d80ab078340e574e100f80c103d45da05337df435b00968153</originalsourceid><addsrcrecordid>eNpdkM1v1DAQxS1ERZfCiTuyxIEDynYcf-6NalUKUj8kWM6W40y6WSXxYicq_Pd4m3aRuIylmd-8eX6EvGOwZKUw535fLaVZMjDmBVkwLnQhy5K_JAsAWBUlV_yUvE5pB1BK0PwVOS1BGVUquSDfN9uISG_xga5drHEIXVtjok0MPb3Bcetyh17-HqPzIw0N_TFin6gbarp5aO_ToXWLsZ16GjrMbYxvyEnjuoRvn94z8vPL5Wb9tbi-u_q2vrguvFJ6LIxXIluQ0nhklagNuAq04QJQaoEMoDHgGfBayNqB5FzXjeCyyp9Shkl-Rj7OuvsYfk2YRtu3yWPXuQHDlKwWZiVWGg7kh__IXZjikM1ZJhQIDtzwTH2aKR9DShEbu49t7-Ify8AekrY5aSuNPSSd6fdPmlPVY31kn6PNwNUM5GnrXReGrh3w32WftN9i3-aNrA8gDRgLTD3K57IqGZO6ZCorfZ6Vdml093g85eLY-g6fbZm5PK4fR1sXLQ78L9CAo8o</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>1460430383</pqid></control><display><type>article</type><title>Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander</title><source>J-STAGE Free</source><source>MEDLINE</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Free Full-Text Journals in Chemistry</source><creator>Bai, Liming ; Zhao, Ming ; Toki, Asami ; Sakai, Jun-ichi ; Yang, Xiao-yang ; Bai, Yuhua ; Ando, Mariko ; Hirose, Katsutoshi ; Ando, Masayoshi</creator><creatorcontrib>Bai, Liming ; Zhao, Ming ; Toki, Asami ; Sakai, Jun-ichi ; Yang, Xiao-yang ; Bai, Yuhua ; Ando, Mariko ; Hirose, Katsutoshi ; Ando, Masayoshi ; cDepartment of Chemistry and Chemical Engineering ; gKNC Laboratories Co ; aCollege of Chemistry and Chemistry Engineering ; Pharmaceutical Department ; Faculty of Engineering ; bGraduate School of Science and Technology ; dAtmospheric Chemistry &amp; Aerosol Division ; Chinese Research Academy of Environmental Science ; Tohoku University ; Ltd ; Qiqihar University ; eDepartment of Medicinal Chemistry ; Daqing Campus of Harbin Medical University ; Niigata University ; School of Engineering ; fTechnical Division</creatorcontrib><description>Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.</description><identifier>ISSN: 0009-2363</identifier><identifier>EISSN: 1347-5223</identifier><identifier>DOI: 10.1248/cpb.58.1088</identifier><identifier>PMID: 20686265</identifier><language>eng</language><publisher>Japan: The Pharmaceutical Society of Japan</publisher><subject>cardenolide B-1 ; cardenolide B-2 ; Cardenolides - chemistry ; Cardenolides - isolation &amp; purification ; Methanol - chemistry ; Molecular Conformation ; Nerium - chemistry ; Nerium oleander ; oleagenin ; Plant Stems - chemistry ; Plants, Medicinal - chemistry ; Stereoisomerism</subject><ispartof>Chemical and Pharmaceutical Bulletin, 2010/08/01, Vol.58(8), pp.1088-1092</ispartof><rights>2010 The Pharmaceutical Society of Japan</rights><rights>Copyright Japan Science and Technology Agency 2010</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c667t-8c64265558ce1b4d80ab078340e574e100f80c103d45da05337df435b00968153</citedby><cites>FETCH-LOGICAL-c667t-8c64265558ce1b4d80ab078340e574e100f80c103d45da05337df435b00968153</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1877,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/20686265$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bai, Liming</creatorcontrib><creatorcontrib>Zhao, Ming</creatorcontrib><creatorcontrib>Toki, Asami</creatorcontrib><creatorcontrib>Sakai, Jun-ichi</creatorcontrib><creatorcontrib>Yang, Xiao-yang</creatorcontrib><creatorcontrib>Bai, Yuhua</creatorcontrib><creatorcontrib>Ando, Mariko</creatorcontrib><creatorcontrib>Hirose, Katsutoshi</creatorcontrib><creatorcontrib>Ando, Masayoshi</creatorcontrib><creatorcontrib>cDepartment of Chemistry and Chemical Engineering</creatorcontrib><creatorcontrib>gKNC Laboratories Co</creatorcontrib><creatorcontrib>aCollege of Chemistry and Chemistry Engineering</creatorcontrib><creatorcontrib>Pharmaceutical Department</creatorcontrib><creatorcontrib>Faculty of Engineering</creatorcontrib><creatorcontrib>bGraduate School of Science and Technology</creatorcontrib><creatorcontrib>dAtmospheric Chemistry &amp; Aerosol Division</creatorcontrib><creatorcontrib>Chinese Research Academy of Environmental Science</creatorcontrib><creatorcontrib>Tohoku University</creatorcontrib><creatorcontrib>Ltd</creatorcontrib><creatorcontrib>Qiqihar University</creatorcontrib><creatorcontrib>eDepartment of Medicinal Chemistry</creatorcontrib><creatorcontrib>Daqing Campus of Harbin Medical University</creatorcontrib><creatorcontrib>Niigata University</creatorcontrib><creatorcontrib>School of Engineering</creatorcontrib><creatorcontrib>fTechnical Division</creatorcontrib><title>Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander</title><title>Chemical &amp; Pharmaceutical Bulletin</title><addtitle>Chem. Pharm. Bull.</addtitle><description>Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.</description><subject>cardenolide B-1</subject><subject>cardenolide B-2</subject><subject>Cardenolides - chemistry</subject><subject>Cardenolides - isolation &amp; purification</subject><subject>Methanol - chemistry</subject><subject>Molecular Conformation</subject><subject>Nerium - chemistry</subject><subject>Nerium oleander</subject><subject>oleagenin</subject><subject>Plant Stems - chemistry</subject><subject>Plants, Medicinal - chemistry</subject><subject>Stereoisomerism</subject><issn>0009-2363</issn><issn>1347-5223</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2010</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkM1v1DAQxS1ERZfCiTuyxIEDynYcf-6NalUKUj8kWM6W40y6WSXxYicq_Pd4m3aRuIylmd-8eX6EvGOwZKUw535fLaVZMjDmBVkwLnQhy5K_JAsAWBUlV_yUvE5pB1BK0PwVOS1BGVUquSDfN9uISG_xga5drHEIXVtjok0MPb3Bcetyh17-HqPzIw0N_TFin6gbarp5aO_ToXWLsZ16GjrMbYxvyEnjuoRvn94z8vPL5Wb9tbi-u_q2vrguvFJ6LIxXIluQ0nhklagNuAq04QJQaoEMoDHgGfBayNqB5FzXjeCyyp9Shkl-Rj7OuvsYfk2YRtu3yWPXuQHDlKwWZiVWGg7kh__IXZjikM1ZJhQIDtzwTH2aKR9DShEbu49t7-Ify8AekrY5aSuNPSSd6fdPmlPVY31kn6PNwNUM5GnrXReGrh3w32WftN9i3-aNrA8gDRgLTD3K57IqGZO6ZCorfZ6Vdml093g85eLY-g6fbZm5PK4fR1sXLQ78L9CAo8o</recordid><startdate>20100801</startdate><enddate>20100801</enddate><creator>Bai, Liming</creator><creator>Zhao, Ming</creator><creator>Toki, Asami</creator><creator>Sakai, Jun-ichi</creator><creator>Yang, Xiao-yang</creator><creator>Bai, Yuhua</creator><creator>Ando, Mariko</creator><creator>Hirose, Katsutoshi</creator><creator>Ando, Masayoshi</creator><general>The Pharmaceutical Society of Japan</general><general>Pharmaceutical Society of Japan</general><general>Japan Science and Technology Agency</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7TK</scope><scope>7TM</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20100801</creationdate><title>Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander</title><author>Bai, Liming ; Zhao, Ming ; Toki, Asami ; Sakai, Jun-ichi ; Yang, Xiao-yang ; Bai, Yuhua ; Ando, Mariko ; Hirose, Katsutoshi ; Ando, Masayoshi</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c667t-8c64265558ce1b4d80ab078340e574e100f80c103d45da05337df435b00968153</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2010</creationdate><topic>cardenolide B-1</topic><topic>cardenolide B-2</topic><topic>Cardenolides - chemistry</topic><topic>Cardenolides - isolation &amp; purification</topic><topic>Methanol - chemistry</topic><topic>Molecular Conformation</topic><topic>Nerium - chemistry</topic><topic>Nerium oleander</topic><topic>oleagenin</topic><topic>Plant Stems - chemistry</topic><topic>Plants, Medicinal - chemistry</topic><topic>Stereoisomerism</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bai, Liming</creatorcontrib><creatorcontrib>Zhao, Ming</creatorcontrib><creatorcontrib>Toki, Asami</creatorcontrib><creatorcontrib>Sakai, Jun-ichi</creatorcontrib><creatorcontrib>Yang, Xiao-yang</creatorcontrib><creatorcontrib>Bai, Yuhua</creatorcontrib><creatorcontrib>Ando, Mariko</creatorcontrib><creatorcontrib>Hirose, Katsutoshi</creatorcontrib><creatorcontrib>Ando, Masayoshi</creatorcontrib><creatorcontrib>cDepartment of Chemistry and Chemical Engineering</creatorcontrib><creatorcontrib>gKNC Laboratories Co</creatorcontrib><creatorcontrib>aCollege of Chemistry and Chemistry Engineering</creatorcontrib><creatorcontrib>Pharmaceutical Department</creatorcontrib><creatorcontrib>Faculty of Engineering</creatorcontrib><creatorcontrib>bGraduate School of Science and Technology</creatorcontrib><creatorcontrib>dAtmospheric Chemistry &amp; Aerosol Division</creatorcontrib><creatorcontrib>Chinese Research Academy of Environmental Science</creatorcontrib><creatorcontrib>Tohoku University</creatorcontrib><creatorcontrib>Ltd</creatorcontrib><creatorcontrib>Qiqihar University</creatorcontrib><creatorcontrib>eDepartment of Medicinal Chemistry</creatorcontrib><creatorcontrib>Daqing Campus of Harbin Medical University</creatorcontrib><creatorcontrib>Niigata University</creatorcontrib><creatorcontrib>School of Engineering</creatorcontrib><creatorcontrib>fTechnical Division</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Neurosciences Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Chemical &amp; Pharmaceutical Bulletin</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bai, Liming</au><au>Zhao, Ming</au><au>Toki, Asami</au><au>Sakai, Jun-ichi</au><au>Yang, Xiao-yang</au><au>Bai, Yuhua</au><au>Ando, Mariko</au><au>Hirose, Katsutoshi</au><au>Ando, Masayoshi</au><aucorp>cDepartment of Chemistry and Chemical Engineering</aucorp><aucorp>gKNC Laboratories Co</aucorp><aucorp>aCollege of Chemistry and Chemistry Engineering</aucorp><aucorp>Pharmaceutical Department</aucorp><aucorp>Faculty of Engineering</aucorp><aucorp>bGraduate School of Science and Technology</aucorp><aucorp>dAtmospheric Chemistry &amp; Aerosol Division</aucorp><aucorp>Chinese Research Academy of Environmental Science</aucorp><aucorp>Tohoku University</aucorp><aucorp>Ltd</aucorp><aucorp>Qiqihar University</aucorp><aucorp>eDepartment of Medicinal Chemistry</aucorp><aucorp>Daqing Campus of Harbin Medical University</aucorp><aucorp>Niigata University</aucorp><aucorp>School of Engineering</aucorp><aucorp>fTechnical Division</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander</atitle><jtitle>Chemical &amp; Pharmaceutical Bulletin</jtitle><addtitle>Chem. Pharm. Bull.</addtitle><date>2010-08-01</date><risdate>2010</risdate><volume>58</volume><issue>8</issue><spage>1088</spage><epage>1092</epage><pages>1088-1092</pages><issn>0009-2363</issn><eissn>1347-5223</eissn><abstract>Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.</abstract><cop>Japan</cop><pub>The Pharmaceutical Society of Japan</pub><pmid>20686265</pmid><doi>10.1248/cpb.58.1088</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 0009-2363
ispartof Chemical and Pharmaceutical Bulletin, 2010/08/01, Vol.58(8), pp.1088-1092
issn 0009-2363
1347-5223
language eng
recordid cdi_proquest_miscellaneous_748949705
source J-STAGE Free; MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Free Full-Text Journals in Chemistry
subjects cardenolide B-1
cardenolide B-2
Cardenolides - chemistry
Cardenolides - isolation & purification
Methanol - chemistry
Molecular Conformation
Nerium - chemistry
Nerium oleander
oleagenin
Plant Stems - chemistry
Plants, Medicinal - chemistry
Stereoisomerism
title Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T16%3A30%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Three%20New%20Cardenolides%20from%20Methanol%20Extract%20of%20Stems%20and%20Twigs%20of%20Nerium%20oleander&rft.jtitle=Chemical%20&%20Pharmaceutical%20Bulletin&rft.au=Bai,%20Liming&rft.aucorp=cDepartment%20of%20Chemistry%20and%20Chemical%20Engineering&rft.date=2010-08-01&rft.volume=58&rft.issue=8&rft.spage=1088&rft.epage=1092&rft.pages=1088-1092&rft.issn=0009-2363&rft.eissn=1347-5223&rft_id=info:doi/10.1248/cpb.58.1088&rft_dat=%3Cproquest_cross%3E3133733851%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1460430383&rft_id=info:pmid/20686265&rfr_iscdi=true