Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander

Three New Cardenolides from Methanol Extract of Stems and Twigs of Nerium oleander

Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.

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Veröffentlicht in:Chemical & Pharmaceutical Bulletin 2010/08/01, Vol.58(8), pp.1088-1092
Hauptverfasser: Bai, Liming, Zhao, Ming, Toki, Asami, Sakai, Jun-ichi, Yang, Xiao-yang, Bai, Yuhua, Ando, Mariko, Hirose, Katsutoshi, Ando, Masayoshi
Format: Artikel
Sprache:eng
Schlagworte:
cardenolide B-1
cardenolide B-2
Cardenolides - chemistry
Cardenolides - isolation & purification
Methanol - chemistry
Molecular Conformation
Nerium - chemistry
Nerium oleander
oleagenin
Plant Stems - chemistry
Plants, Medicinal - chemistry
Stereoisomerism
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Zusammenfassung:Two new cardenolide monoglycosides, cardenolides B-1 (1) and B-2 (2) were isolated from Nerium oleander, together with oleagenin (3) which is the first isolated compound from natural sources. The structure of compounds 1—3 were established on the basis of their spectroscopic data.
ISSN:0009-2363
1347-5223
DOI:10.1248/cpb.58.1088