At a crossroads in oncology

At a crossroads in oncology

We survey the current paradigm for cancer therapy and offer a perspective on the state of clinical oncology. Next, we address the key clinical and biological obstacles that have hampered progress to date. Recent insights into the true genetic complexity of cancer, the mixed clinical performance of t...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Current opinion in pharmacology 2010-08, Vol.10 (4), p.356-361
1. Verfasser: Kamb, Alexander
Format: Artikel
Sprache:eng
Schlagworte:
Antineoplastic Agents - pharmacology
Antineoplastic Agents - therapeutic use
Apoptosis - drug effects
Biomedical Research
Cell Movement - drug effects
Cell Proliferation - drug effects
Drug Discovery
Humans
Immunotherapy
Internal Medicine
Medical Education
Neoplasms - genetics
Neoplasms - immunology
Neoplasms - therapy
Neovascularization, Pathologic - drug therapy
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:We survey the current paradigm for cancer therapy and offer a perspective on the state of clinical oncology. Next, we address the key clinical and biological obstacles that have hampered progress to date. Recent insights into the true genetic complexity of cancer, the mixed clinical performance of targeted therapies, and the homogeneity of industry pipelines argue for new approaches to cancer therapy.
ISSN:1471-4892
1471-4973
DOI:10.1016/j.coph.2010.05.006