In vitro efficacy of Ingavirin against the pandemic influenza virus A(H1N1/09)v

In vitro efficacy of Ingavirin against the pandemic influenza virus A(H1N1/09)v

Ingavirin was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v, as well as the strains A/Chicken/Kurgan/05/2005 (H5N1) and A/Aichi/2/68 (H3N2) in the MDCK cell cultur...

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Veröffentlicht in:Antibiotiki i himioterapiâ 2010-01, Vol.55 (3-4), p.12-16
Hauptverfasser: Shishkina, L N, Nebol'sin, V E, Kabanov, A S, Skarnovich, M O, Erdyneeva, U B, Mazurkova, N A, Serova, O A, Stavskiĭ, E A, Drozdov, I G
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Sprache:rus
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Zusammenfassung:Ingavirin was shown to be efficient in inhibition of the influenza virus strains A/California/04/2009 (H1N1)v, A/California/07/2009 (H1N1)v, A/Moscow/225/2009 (H1N1)v and A/Moscow/226/2009 (H1N1)v, as well as the strains A/Chicken/Kurgan/05/2005 (H5N1) and A/Aichi/2/68 (H3N2) in the MDCK cell culture. The hemagglutinin and cytopathic activity of the influenza virus strains decreased at entering Ingavirin in vitro.
ISSN:0235-2990