Induction of sister chromatid exchanges by nicotinamide in Chinese hamster lung fibroblasts and human lymphoblastoid cells

Nicotinamide, which occurs naturally, produced sister chromatid exchanges in Chinese hamster lung fibroblasts and human lymphoblastoid cells. The inductions were dose-dependent with concentrations of 1.0–10.0 mM nicotinamide. Elastatinal, a protease inhibitor that has been reported to suppress induc...

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Veröffentlicht in:	Biochemical and biophysical research communications 1979-10, Vol.90 (4), p.1147-1152
Hauptverfasser:	Utakoji, Tadashi, Hosoda, Keiko, Umezawa, Kazuo, Sawamura, Mutsuko, Matsushima, Taijiro, Miwa, Masanao, Sugimura, Takashi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line Cricetinae Cricetulus Crossing Over, Genetic - drug effects Dose-Response Relationship, Drug Humans Lung Lymphocytes Niacinamide - pharmacology Sister Chromatid Exchange - drug effects
Online-Zugang:	Volltext
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