Adult Hodgkin's disease in Uganda

A retrospective analysis of 26 cases recorded in Kampala Cancer Registry over a 5‐year period and a prospective study of 18 patients admitted to Mulago Hospital since July 1968 were carried out. Clinical and histopathologic features and response to combination chemotherapy were investigated. Hodgkin's disease in Uganda commonly affects children and young adults, particularly males, and is a more aggressive disease than seen elsewhere, both with respect to clinical stage and histopathology. Combination chemotherapy is an effective form of therapy and induced complete remission in 13 of 17 patients (76%), all but three of whom had Stage IV disease.