Specificity of Allogeneic Cell Recognition by Human Lymphocytes in vitro

Specificity of Allogeneic Cell Recognition by Human Lymphocytes in vitro

Human lymphocytes proliferate in vitro in response to foreign histocompatibility antigens that are present on allogeneic lymphocytes. Within a population of immunocompetent lymphocytes there are specific subpopulations that respond to allogeneic cells from different individuals. A means of selective...

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Veröffentlicht in:Science (American Association for the Advancement of Science) 1971-06, Vol.172 (3990), p.1350-1352
Hauptverfasser: Zoschke, David C., Bach, Fritz H.
Format: Artikel
Sprache:eng
Schlagworte:
Antigens
Bromodeoxyuridine - metabolism
Cell growth
Cell separation
Cellular immunity
Culture Techniques
Cultured cells
DNA - biosynthesis
Graft vs Host Reaction
Histocompatibility
Humans
Isoantigens
Lymphocytes
Lymphocytes - immunology
Mixed lymphocyte culture test
Pluripotent stem cells
Stem cells
Thymidine - metabolism
Totipotent stem cells
Tritium
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Beschreibung
Zusammenfassung:Human lymphocytes proliferate in vitro in response to foreign histocompatibility antigens that are present on allogeneic lymphocytes. Within a population of immunocompetent lymphocytes there are specific subpopulations that respond to allogeneic cells from different individuals. A means of selectively eliminating such subpopulations is suggested.
ISSN:0036-8075
1095-9203
DOI:10.1126/science.172.3990.1350