Enzymic Formation of norAdrenaline in Mammalian Tissue Extracts

Enzymic Formation of norAdrenaline in Mammalian Tissue Extracts

THE possibility that nor adrenaline carboxylic acid, 3,4-dihydroxyphenylserine, might be a precursor of adrenaline has been suggested previously 1 . Recently, it has found experimental support 2 . Experiments carried out in Oxford 3 have shown that lævo- nor -adrenaline was formed when the amino-aci...

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Veröffentlicht in:Nature (London) 1950-06, Vol.165 (4206), p.926-926
Hauptverfasser: BEYER, KARL H., BLASCHKO, H., BURN, J. H., LANGEMANN, H.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Biochemical Phenomena
Biochemistry
Humanities and Social Sciences
letter
Mammals
multidisciplinary
Norepinephrine
Old Medline
Science
Science (multidisciplinary)
Tissue Extracts
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Beschreibung
Zusammenfassung:THE possibility that nor adrenaline carboxylic acid, 3,4-dihydroxyphenylserine, might be a precursor of adrenaline has been suggested previously 1 . Recently, it has found experimental support 2 . Experiments carried out in Oxford 3 have shown that lævo- nor -adrenaline was formed when the amino-acid was decarboxylated by bacterial preparations; but no similar reaction was observed in mammalian tissue extracts.
ISSN:0028-0836
1476-4687
DOI:10.1038/165926a0