Plasminogen Activator Production by Human Monocytes: I. Enhancement by Activated Lymphocytes and Lymphocyte Products

Human monocytes, but not nylon wool column-nonadherent lymphocytes, produce plasminogen activator. The activity is found only in association with intact cells. Exposure of monocytes to activated lymphocytes or to lymphokine-rich supernatants enhances monocyte plasminogen activator production. The as...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	The Journal of immunology (1950) 1979-12, Vol.123 (6), p.2808-2813
Hauptverfasser:	Greineder, Dirk K, Connorton, Kevin J, David, John R
Format:	Artikel
Sprache:	eng
Schlagworte:	Antigens, Bacterial Cell Communication Fibrinolysis Humans Lymphocyte Activation Lymphocytes - immunology Lymphokines - pharmacology Monocytes - metabolism Phytohemagglutinins - pharmacology Plasminogen Activators - biosynthesis Tetanus Toxoid - immunology Tuberculin - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Human monocytes, but not nylon wool column-nonadherent lymphocytes, produce plasminogen activator. The activity is found only in association with intact cells. Exposure of monocytes to activated lymphocytes or to lymphokine-rich supernatants enhances monocyte plasminogen activator production. The assay allows assessment of baseline and activated human monocyte function.
ISSN:	0022-1767 1550-6606