Specificity of Radioiodinated (I131) Immune Globulin As Determined by Quantitative Precipitin Reaction

The reaction between human serum albumin and I131 trace iodinated rabbit antibody was studied by the quantitative precipitin reaction. The amount of radioactivity found in each immune precipitate was proportional to the antibody nitrogen precipitated. Under the iodinating conditions described (1.3 i...

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Veröffentlicht in:	The Journal of immunology (1950) 1951-03, Vol.66 (3), p.297-302
Hauptverfasser:	Masouredis, S. P, Melcher, L. R, Koblick, D. C
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Immunoglobulins Old Medline Precipitins
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Beschreibung
Zusammenfassung:	The reaction between human serum albumin and I131 trace iodinated rabbit antibody was studied by the quantitative precipitin reaction. The amount of radioactivity found in each immune precipitate was proportional to the antibody nitrogen precipitated. Under the iodinating conditions described (1.3 iodine atoms per antibody molecule) no loss of immunologic specificity of rabbit antibody labelled with I131 was demonstrated.
ISSN:	0022-1767 1550-6606
DOI:	10.4049/jimmunol.66.3.297