Cell-mediated immunity in Darier's disease

Cell-mediated immunity in Darier's disease

Darier's disease, often complicated by skin infections, has been linked with a depressed cell-mediated immunity. Four moderate to severely affected patients with a negative history of skin infections were studied. T cell function was evaluated by Standard delayed hypersensitivity skin tests, en...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Journal of the American Academy of Dermatology 1979-10, Vol.1 (4), p.348-351
Hauptverfasser: Henry, John C., Padilla, R. Steven, Becker, Larry E., Bankhurst, Arthur D.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Darier Disease - immunology
Female
Humans
Immunity, Cellular
Leukocyte Count
Lymphocyte Activation
Male
Middle Aged
Skin Tests
T-Lymphocytes
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:Darier's disease, often complicated by skin infections, has been linked with a depressed cell-mediated immunity. Four moderate to severely affected patients with a negative history of skin infections were studied. T cell function was evaluated by Standard delayed hypersensitivity skin tests, enumeration of peripheral T cells, and mitogen-stimulated proliferation assays. No defect in cell-mediated immunity was found. The significance of the results when compared with prior studies is discussed.
ISSN:0190-9622
1097-6787
DOI:10.1016/S0190-9622(79)70028-4