Malignancy in a 19-year experience of adult celiac disease

Malignancy has developed in 10 of 93 patients with celiac disease who attended this hospital from 1959 to 1978. Four patients developed lymphoma, 5 a squamous carcinoma of the esophagus, and 1 an adenocarcinoma of the ileum. Because the majority of patients were ingesting varying amounts of gluten a...

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Veröffentlicht in:	Digestive diseases and sciences 1979-09, Vol.24 (9), p.684-688
Hauptverfasser:	Selby, W S, Gallagher, N D
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - complications Adenocarcinoma - epidemiology Adolescent Adult Aged Australia Carcinoma, Squamous Cell - complications Carcinoma, Squamous Cell - epidemiology Celiac Disease - complications Celiac Disease - diet therapy Esophageal Neoplasms - complications Esophageal Neoplasms - epidemiology Female Glutens Humans Ileum Intestinal Neoplasms - complications Intestinal Neoplasms - epidemiology Lymphoma - complications Lymphoma - epidemiology Male Middle Aged Risk
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Zusammenfassung:	Malignancy has developed in 10 of 93 patients with celiac disease who attended this hospital from 1959 to 1978. Four patients developed lymphoma, 5 a squamous carcinoma of the esophagus, and 1 an adenocarcinoma of the ileum. Because the majority of patients were ingesting varying amounts of gluten at the time of their follow-up no conclusion can be drawn about the possible role of a gluten-free diet in the prevention of malignancy.
ISSN:	0163-2116 1573-2568
DOI:	10.1007/BF01314465