Cancer therapy with localized hyperthermia using an invasive microwave system

Cancer therapy with localized hyperthermia using an invasive microwave system

A system has been developed for producing local hyperthermia in small animal tumors by means of an invasive needle microwave antenna. Thermal distributions produced by this system using 1 GHz microwaves have been characterized in mammary adenocarcinomas (MTG-B) implanted in thighs of C3H mice. Thera...

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Veröffentlicht in:Journal of microwave power 1979-06, Vol.14 (2), p.181-186
Hauptverfasser: Douple, E B, Srohbehn, J W, Bowers, E D, Walsh, J E
Format: Artikel
Sprache:eng
Schlagworte:
Adenocarcinoma - therapy
Animals
Diathermy - instrumentation
Diathermy - methods
Female
Mammary Neoplasms, Experimental - therapy
Mice
Mice, Inbred C3H
Neoplasm Transplantation
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Zusammenfassung:A system has been developed for producing local hyperthermia in small animal tumors by means of an invasive needle microwave antenna. Thermal distributions produced by this system using 1 GHz microwaves have been characterized in mammary adenocarcinomas (MTG-B) implanted in thighs of C3H mice. Therapeutic efficacy by hyperthermia was demonstrated by comparing MTG-B diameters in mice following control, sham or hyperthermia treatment. It is proposed that this system could be employed clinically to provide very local hyperthermia in deep-seated tumors.
ISSN:0022-2739