Effects of Exogenous Ubiquinone-10 on Endogenous Ubiquinone-10 in Canine Plasma and on Electron Transport Enzymes in Leucocytes

Effects of Exogenous Ubiquinone-10 on Endogenous Ubiquinone-10 in Canine Plasma and on Electron Transport Enzymes in Leucocytes

The distribution of exogenous ubiquinone-10 in canine plasma was examined using deuterium-labeled ubiquinone-10 in conjunction with a computerized gas chromatographmass spectrometry system. Electron transport enzymes in canine leucocytes were also studied. An increase in the plasma level of exogenou...

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Veröffentlicht in:Chemical & pharmaceutical bulletin 1979/05/25, Vol.27(5), pp.1101-1105
Hauptverfasser: NAKAMURA, TETSUYA, SANMA, HIDEYUKI, IMABAYASHI, SUKEHIRO, SAWA, YOSHIO, HAMAMURA, KIMIO
Format: Artikel
Sprache:eng
Schlagworte:
Animals
canine leucocytes
Dogs
Electron Transport - drug effects
In Vitro Techniques
Leukocytes - drug effects
Leukocytes - enzymology
Ubiquinone - blood
Ubiquinone - pharmacology
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container_end_page 1105
container_issue 5
container_start_page 1101
container_title Chemical & pharmaceutical bulletin
container_volume 27
creator NAKAMURA, TETSUYA
SANMA, HIDEYUKI
IMABAYASHI, SUKEHIRO
SAWA, YOSHIO
HAMAMURA, KIMIO
description The distribution of exogenous ubiquinone-10 in canine plasma was examined using deuterium-labeled ubiquinone-10 in conjunction with a computerized gas chromatographmass spectrometry system. Electron transport enzymes in canine leucocytes were also studied. An increase in the plasma level of exogenous ubiquinone-10 did not affect the level of endogenous ubiquinone-10, and it was reflected in increased activities of the electron transport enzymes (succinate dehydrogenase Co Q reductase, succinate cytochrome c reductase and succinate oxidase) in leucocytes.
doi_str_mv 10.1248/cpb.27.1101
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source MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese; Free Full-Text Journals in Chemistry
subjects Animals
canine leucocytes
Dogs
Electron Transport - drug effects
In Vitro Techniques
Leukocytes - drug effects
Leukocytes - enzymology
Ubiquinone - blood
Ubiquinone - pharmacology
title Effects of Exogenous Ubiquinone-10 on Endogenous Ubiquinone-10 in Canine Plasma and on Electron Transport Enzymes in Leucocytes
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