Uniform Transfer to Random Bred Rats of Lymphatic Leukemia Induced by Gastric Instillation of Methylcholanthrene

Summary Lymphatic leukemia induced in Wistar rats by the gastric instillation of methylcholanthrene, was transferred to 40-day-old animals of our random bred Wistar colony with only indifferent success. When transfers were made to animals not older than 7 days, these were successful in 100% of the animals. Transfer of the leukemia was also made uniformly to equally young animals of the Sherman and Long-Evans strains. The intraperitoneal injection of leukemic spleen cells was used in these experiments.