Chromosomal marker 20q- in cases of osteomyelosclerosis and CML

Two male patients with myeloproliferative disorders (osteomyelosclerosis in one and CML in the other) were found to have a chromosomal marker 20q- in blood cells (unstimulated short time cultures). Marked erythropoietic disturbances were not revealed in these cases. The specificity of the 20q- marke...

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Veröffentlicht in:	Human genetics 1979-01, Vol.50 (1), p.101-104
Hauptverfasser:	Fleischman, E W, Prigogina, E L, Volkova, M A, Kulagina, O E
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Chromosome Deletion Chromosomes, Human, 19-20 Erythropoiesis Humans Leukemia, Myeloid - genetics Male Middle Aged Primary Myelofibrosis - genetics
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Zusammenfassung:	Two male patients with myeloproliferative disorders (osteomyelosclerosis in one and CML in the other) were found to have a chromosomal marker 20q- in blood cells (unstimulated short time cultures). Marked erythropoietic disturbances were not revealed in these cases. The specificity of the 20q- marker for red cell disorders is discussed.
ISSN:	0340-6717 1432-1203
DOI:	10.1007/BF00295596