HLA antigens in familial Hodgkin's disease

HLA antigens in familial Hodgkin's disease

In a study of 13 families prone to Hodgkin's disease, the probands showed significant excesses of the HLA antigens Bw35 (7 cases) and Bw37 (3 cases). Although based on a small number of patients, the results suggest that immunogenetic mechanisms account at least partly for the familial predispo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:International journal of cancer 1979-06, Vol.23 (6), p.777-780
Hauptverfasser: Greene, Mark H., McKeen, Elisabeth A., Li, Frederick P., Blattner, William A., Fraumeni, Joseph F.
Format: Artikel
Sprache:eng
Schlagworte:
Adolescent
Adult
Aged
Child, Preschool
Female
HLA Antigens
Hodgkin Disease - genetics
Hodgkin Disease - immunology
Humans
Male
Middle Aged
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:In a study of 13 families prone to Hodgkin's disease, the probands showed significant excesses of the HLA antigens Bw35 (7 cases) and Bw37 (3 cases). Although based on a small number of patients, the results suggest that immunogenetic mechanisms account at least partly for the familial predisposition to Hodgkin's disease.
ISSN:0020-7136
1097-0215
DOI:10.1002/ijc.2910230607