The Cellular Transfer of Cutaneous Hypersensitivity to Tuberculin in Man

Summary and Conclusion 1. It has been possible to passively transfer in 12 consecutive instances cutaneous tuberculin hypersensitivity to tuberculin negative human recipients by means of an intradermal injection of viable leucocytes obtained from the blood of tuberculin positive human donors. 2. The effort at the passive transfer of cutaneous tuberculin hypersensitivity was unsuccessful when the leucocytes used, in the transfer were obtained from tuberculin negative donors. 3. The induced cutaneous hypersensitivity to tuberculin is a transient phenomenon of 4 days to 3 months duration, which can be produced again in the same individual. 4. The degree of induced hypersensitivity to tuberculin seems to bear a relationship to the dosage of leucocytes used and the degree of tuberculin hypersensitivity of the leucocyte donor.