On the possible role of glutathione in maintaining human lens protein sulphydryls

Glutathione can cleave the disulphide bonds in proteins from advanced nuclear cataractous lenses and in mixed disulphides of lens proteins and glutathione. The equilibrium constants for these reactions were estimated to be 0·02-0·05 and 0·07 respectively. Endogenous glutathione can protect lens prot...

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Veröffentlicht in:	Experimental eye research 1979-06, Vol.28 (6), p.665-671
1. Verfasser:	Augusteyn, R.C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cataract - metabolism Crystallins - metabolism Disulfides - metabolism glutathione Glutathione - physiology human lens protein sulphydryl Humans nuclear cataract Sulfhydryl Compounds - metabolism Time Factors
Online-Zugang:	Volltext
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