Observations on staphylococcal infections treated with aureomycin

Five infants with staphylococcal infections who had shown no clinical response to penicillin and sulfadiazine were successfully treated with aureomycin in the summer of 1948. Marked improvement was noted in all patients within 48 hours. The sixth patient, who was critically ill with staphylococcal septicemia and had not responded to combined penicillin, streptomycin and sulfonamide therapy, had negative blood cultures after five days of aureomycin therapy and made a rapid, uneventful recovery. No toxic effects from the drug were apparent.