Cover Picture: Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile (ChemMedChem 10/2008)

Cover Picture: Computational Studies to Discover a New NR2B/NMDA Receptor Antagonist and Evaluation of Pharmacological Profile (ChemMedChem 10/2008)

The cover picture shows the best docking result of a new noncompetitive NMDA receptor antagonist, 2-(4-benzylpiperidin-1-yl)-1-(1H-indol-3-yl)ethan-1-one, in the NR2B ifenprodil-like binding site model. For details, see the Full Paper by A. Chimirri et al. on p. 1539 ff.

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Bibliographische Detailangaben
Veröffentlicht in:ChemMedChem 2008-10, Vol.3 (10), p.1465-1465
Hauptverfasser: Gitto, Rosaria, De Luca, Laura, Ferro, Stefania, Occhiuto, Francesco, Samperi, Stefania, De Sarro, Giovanbattista, Russo, Emilio, Ciranna, Lucia, Costa, Lara, Chimirri, Alba
Format: Artikel
Sprache:eng
Schlagworte:
anticonvulsant activity
HCN-1A neurons
molecular modeling
neurotransmitters
NR2B/NMDA antagonists
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Zusammenfassung:The cover picture shows the best docking result of a new noncompetitive NMDA receptor antagonist, 2-(4-benzylpiperidin-1-yl)-1-(1H-indol-3-yl)ethan-1-one, in the NR2B ifenprodil-like binding site model. For details, see the Full Paper by A. Chimirri et al. on p. 1539 ff.
ISSN:1860-7179
1860-7187
DOI:10.1002/cmdc.200890038