EFFECTS OF ANESTHETIC PROTOCOL ON NORMAL CANINE BRAIN UPTAKE OF 18F-FDG ASSESSED BY PET/CT

The purpose of this study was to assess the effects of four anesthetic protocols on normal canine brain uptake of 2‐deoxy‐2‐[18F]fluoro‐d‐glucose (FDG) using positron emission tomography/computed tomography (PET/CT). Five clinically normal beagle dogs were anesthetized with (1) propofol/isoflurane,...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Veterinary radiology & ultrasound 2010-03, Vol.51 (2), p.130-135
Hauptverfasser:	LEE, MIN SU, KO, JEFF, LEE, AH RA, LEE, IN HYE, JUNG, MI AE, AUSTIN, BRENDA, CHUNG, HYUNWOO, NAHM, SANGSOEP, EOM, KIDONG
Format:	Artikel
Sprache:	eng
Schlagworte:	18F-FDG Adjuvants, Anesthesia Adrenergic alpha-Agonists anesthesia Anesthetics, Combined Anesthetics, Dissociative Anesthetics, Inhalation Anesthetics, Intravenous Animals Brain - diagnostic imaging Brain - metabolism brain glucose uptake Cross-Over Studies dog Dogs - metabolism Female Fluorodeoxyglucose F18 - administration & dosage Fluorodeoxyglucose F18 - pharmacokinetics Isoflurane Ketamine Male Medetomidine PET/CT Positron-Emission Tomography - veterinary Propofol Radiopharmaceuticals - administration & dosage Radiopharmaceuticals - pharmacokinetics SUV Tiletamine Tomography, X-Ray Computed Xylazine
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The purpose of this study was to assess the effects of four anesthetic protocols on normal canine brain uptake of 2‐deoxy‐2‐[18F]fluoro‐d‐glucose (FDG) using positron emission tomography/computed tomography (PET/CT). Five clinically normal beagle dogs were anesthetized with (1) propofol/isoflurane, (2) medetomidine/pentobarbital, (3) xylazine/ketamine, and (4) medetomidine/tiletamine–zolazepam in a randomized cross‐over design. The standard uptake value (SUV) of FDG was obtained in the frontal, parietal, temporal and occipital lobes, cerebellum, brainstem and whole brain, and compared within and between anesthetic protocols using the Friedman test with significance set at P
ISSN:	1058-8183 1740-8261
DOI:	10.1111/j.1740-8261.2009.01636.x