Platelet-Rich Plasma: From Basic Science to Clinical Applications

Platelet-Rich Plasma: From Basic Science to Clinical Applications

Platelet-rich plasma (PRP) has been utilized in surgery for 2 decades; there has been a recent interest in the use of PRP for the treatment of sports-related injuries. PRP contains growth factors and bioactive proteins that influence the healing of tendon, ligament, muscle, and bone. This article ex...

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Veröffentlicht in:The American journal of sports medicine 2009-11, Vol.37 (11), p.2259-2272
Hauptverfasser: Foster, Timothy E., Puskas, Brian L., Mandelbaum, Bert R., Gerhardt, Michael B., Rodeo, Scott A.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Athletic Injuries - therapy
Biological and medical sciences
Blood platelets
Diseases of the osteoarticular system
Human growth
Humans
Medical sciences
Orthopedic Procedures
Orthopedics
Plasma
Platelet-Rich Plasma
Plateletpheresis
Sports injuries
Sports medicine
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Zusammenfassung:Platelet-rich plasma (PRP) has been utilized in surgery for 2 decades; there has been a recent interest in the use of PRP for the treatment of sports-related injuries. PRP contains growth factors and bioactive proteins that influence the healing of tendon, ligament, muscle, and bone. This article examines the basic science of PRP, and it describes the current clinical applications in sports medicine. This study reviews and evaluates the human studies that have been published in the orthopaedic surgery and sports medicine literature. The use of PRP in amateur and professional sports is reviewed, and the regulation of PRP by antidoping agencies is discussed.
ISSN:0363-5465
1552-3365
DOI:10.1177/0363546509349921