The importance of cholinergic tone in the release of pancreatic polypeptide by gut hormones in man

The importance of cholinergic tone in the release of pancreatic polypeptide by gut hormones in man

The pancreatic polypeptide response to both caerulein and Boots' secretin was greatly obtuned by prior administration of atropine. In addition basal plasma PP concentration fell by 54 ± 7% (mean ± SEM p < 0.001) 30 minutes after atropinisation. Some degree of cholinergic tone thus appears es...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Life sciences (1973) 1979-05, Vol.24 (21), p.1989-1993
Hauptverfasser: Adrian, T.E., Besterman, H.S., Bloom, S.R.
Format: Artikel
Sprache:eng
Schlagworte:
Adult
Atropine
Ceruletide
Humans
Kinetics
Male
Pancreatic Polypeptide - blood
Secretin
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The pancreatic polypeptide response to both caerulein and Boots' secretin was greatly obtuned by prior administration of atropine. In addition basal plasma PP concentration fell by 54 ± 7% (mean ± SEM p < 0.001) 30 minutes after atropinisation. Some degree of cholinergic tone thus appears essential both for maintaining basal PP levels and for the response to gut hormones.
ISSN:0024-3205
1879-0631
DOI:10.1016/0024-3205(79)90310-2