Structural analysis of lipopolysaccharides from Gram-negative bacteria

This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biologic...

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Veröffentlicht in:Biochemistry (Moscow) 2010-04, Vol.75 (4), p.383-404
Hauptverfasser: Kabanov, D. S, Prokhorenko, I. R
Format: Artikel
Sprache:eng
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Zusammenfassung:This review covers data on composition and structure of lipid A, core, and O-polysaccharide of the known lipopolysaccharides from Gram-negative bacteria. The relationship between the structure and biological activity of lipid A is discussed. The data on roles of core and O-polysaccharide in biological activities of lipopolysaccharides are presented. The structural homology of some oligosaccharide sequences of lipopolysaccharides to gangliosides of human cell membranes is considered.
ISSN:0006-2979
1608-3040
DOI:10.1134/S0006297910040012