Kendall’s tau-type rank statistics in genome data
High-dimensional data models abound in genomics studies, where often inadequately small sample sizes create impasses for incorporation of standard statistical tools. Conventional assumptions of linearity of regression, homoscedasticity and (multi-) normality of errors may not be tenable in many such...
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Veröffentlicht in: | Applications of mathematics (Prague) 2008-06, Vol.53 (3), p.207-221 |
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Hauptverfasser: | , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | High-dimensional data models abound in genomics studies, where often inadequately small sample sizes create impasses for incorporation of standard statistical tools. Conventional assumptions of linearity of regression, homoscedasticity and (multi-) normality of errors may not be tenable in many such interdisciplinary setups. In this study, Kendall’s tau-type rank statistics are employed for statistical inference, avoiding most of parametric assumptions to a greater extent. The proposed procedures are compared with Kendall’s tau statistic based ones. Applications in microarray data models are stressed. |
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ISSN: | 0862-7940 1572-9109 |
DOI: | 10.1007/s10492-008-0005-1 |