Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography
Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse‐phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast...
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Veröffentlicht in: | Angewandte Chemie (International ed.) 2009-12, Vol.48 (52), p.9901-9904 |
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container_title | Angewandte Chemie (International ed.) |
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creator | deKrafft, Kathryn E Xie, Zhigang Cao, Guohua Tran, Sylvie Ma, Liqing Zhou, Otto Z Lin, Wenbin |
description | Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse‐phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast agents for computed tomography (CT), as demonstrated by phantom studies (see figure). |
doi_str_mv | 10.1002/anie.200904958 |
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The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast agents for computed tomography (CT), as demonstrated by phantom studies (see figure).</description><subject>computed tomography</subject><subject>contrast agents</subject><subject>Contrast Media - chemistry</subject><subject>coordination polymers</subject><subject>Crystallography, X-Ray</subject><subject>iodine</subject><subject>Iodine - chemistry</subject><subject>Molecular Conformation</subject><subject>nanoparticles</subject><subject>Nanoparticles - chemistry</subject><subject>Polymers - chemistry</subject><subject>Tomography, X-Ray Computed</subject><issn>1433-7851</issn><issn>1521-3773</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2009</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkEtv2zAQhIkiQZOmvfbY6NaTXFJ8Hw03DwOBGyAOeitBiyuXiSQ6pIzW_750ZKS55bSLwTeD3UHoM8ETgnH1zfYeJhXGGjPN1Tt0SnhFSiolPco7o7SUipMT9CGlh8wrhcV7dEK0plIpeop-zYPzvR3AFQvbh1TbFopZCPFZ9aEvbkO76yCmwqa8D9AP3rYZ6Ydo01BM11lJRRNi1rrNdp-0DF1YR7v5vfuIjhvbJvh0mGfo_vJiObsub35czWfTm7LmmKmysqTWmFAHK0edUmpFtZLWucrlk2GFlRDcYSor1RDCmOTESWCSChAWBKFn6OuYu4nhaQtpMJ1PNbSt7SFsk5FMYI4142-TlFWY5P4yORnJOoaUIjRmE31n484QbPblm3355qX8bPhyiN6uOnD_8UPbGdAj8Me3sHsjzkwX84vX4eXo9WmAvy9eGx-NkFRy83NxZcj3pV6w2ztzmfnzkW9sMHYdfTL3d_kzmp8jSktB_wHMd6lB</recordid><startdate>20091221</startdate><enddate>20091221</enddate><creator>deKrafft, Kathryn E</creator><creator>Xie, Zhigang</creator><creator>Cao, Guohua</creator><creator>Tran, Sylvie</creator><creator>Ma, Liqing</creator><creator>Zhou, Otto Z</creator><creator>Lin, Wenbin</creator><general>Wiley-VCH Verlag</general><general>WILEY-VCH Verlag</general><general>WILEY‐VCH Verlag</general><scope>FBQ</scope><scope>BSCLL</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>7QO</scope><scope>8FD</scope><scope>FR3</scope><scope>P64</scope></search><sort><creationdate>20091221</creationdate><title>Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography</title><author>deKrafft, Kathryn E ; Xie, Zhigang ; Cao, Guohua ; Tran, Sylvie ; Ma, Liqing ; Zhou, Otto Z ; Lin, Wenbin</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5048-2a1c9013debd3d888b3987add2d288eb08665d03728f1144751d7e4736e6ae613</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2009</creationdate><topic>computed tomography</topic><topic>contrast agents</topic><topic>Contrast Media - chemistry</topic><topic>coordination polymers</topic><topic>Crystallography, X-Ray</topic><topic>iodine</topic><topic>Iodine - chemistry</topic><topic>Molecular Conformation</topic><topic>nanoparticles</topic><topic>Nanoparticles - chemistry</topic><topic>Polymers - chemistry</topic><topic>Tomography, X-Ray Computed</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>deKrafft, Kathryn E</creatorcontrib><creatorcontrib>Xie, Zhigang</creatorcontrib><creatorcontrib>Cao, Guohua</creatorcontrib><creatorcontrib>Tran, Sylvie</creatorcontrib><creatorcontrib>Ma, Liqing</creatorcontrib><creatorcontrib>Zhou, Otto Z</creatorcontrib><creatorcontrib>Lin, Wenbin</creatorcontrib><collection>AGRIS</collection><collection>Istex</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>Biotechnology Research Abstracts</collection><collection>Technology Research Database</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><jtitle>Angewandte Chemie (International ed.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>deKrafft, Kathryn E</au><au>Xie, Zhigang</au><au>Cao, Guohua</au><au>Tran, Sylvie</au><au>Ma, Liqing</au><au>Zhou, Otto Z</au><au>Lin, Wenbin</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography</atitle><jtitle>Angewandte Chemie (International ed.)</jtitle><addtitle>Angewandte Chemie International Edition</addtitle><date>2009-12-21</date><risdate>2009</risdate><volume>48</volume><issue>52</issue><spage>9901</spage><epage>9904</epage><pages>9901-9904</pages><issn>1433-7851</issn><eissn>1521-3773</eissn><abstract>Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse‐phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast agents for computed tomography (CT), as demonstrated by phantom studies (see figure).</abstract><cop>Weinheim</cop><pub>Wiley-VCH Verlag</pub><pmid>19937883</pmid><doi>10.1002/anie.200904958</doi><tpages>4</tpages></addata></record> |
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subjects | computed tomography contrast agents Contrast Media - chemistry coordination polymers Crystallography, X-Ray iodine Iodine - chemistry Molecular Conformation nanoparticles Nanoparticles - chemistry Polymers - chemistry Tomography, X-Ray Computed |
title | Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography |
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