Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography

Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse‐phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast...

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Veröffentlicht in:Angewandte Chemie (International ed.) 2009-12, Vol.48 (52), p.9901-9904
Hauptverfasser: deKrafft, Kathryn E, Xie, Zhigang, Cao, Guohua, Tran, Sylvie, Ma, Liqing, Zhou, Otto Z, Lin, Wenbin
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container_end_page 9904
container_issue 52
container_start_page 9901
container_title Angewandte Chemie (International ed.)
container_volume 48
creator deKrafft, Kathryn E
Xie, Zhigang
Cao, Guohua
Tran, Sylvie
Ma, Liqing
Zhou, Otto Z
Lin, Wenbin
description Nanoscale coordination polymers (NCPs), prepared with metal ions and an iodinated ligand, were synthesized using reverse‐phase microemulsion techniques and rapid precipitation procedures. The NCPs carry high payloads of iodine (ca. 63 wt %) and have potential applications as a new class of contrast agents for computed tomography (CT), as demonstrated by phantom studies (see figure).
doi_str_mv 10.1002/anie.200904958
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source MEDLINE; Wiley Online Library Journals Frontfile Complete
subjects computed tomography
contrast agents
Contrast Media - chemistry
coordination polymers
Crystallography, X-Ray
iodine
Iodine - chemistry
Molecular Conformation
nanoparticles
Nanoparticles - chemistry
Polymers - chemistry
Tomography, X-Ray Computed
title Iodinated Nanoscale Coordination Polymers as Potential Contrast Agents for Computed Tomography
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