The ultrastructural study of tumorigenic cells using nanobiomarkers

Despite recent advances, patients with malignant brain tumors still have a poor prognosis. Glioblastoma (WHO grade 4 astrocytoma), the most malignant brain tumor, represents 50% of all astrocytomas, with a median survival rate of

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Bibliographische Detailangaben
Veröffentlicht in:	Cancer biotherapy & radiopharmaceuticals 2010-06, Vol.25 (3), p.289-298
Hauptverfasser:	Pavon, Lorena Favaro, Marti, Luciana Cavalheiro, Sibov, Tatiana Tais, Malheiros, Suzana M F, Oliveira, Daniela Mara, Guilhen, Daiane Donna, Camargo-Mathias, Maria Izabel, Amaro Junior, Edson, Gamarra, Lionel Fernel
Format:	Artikel
Sprache:	eng
Schlagworte:	AC133 Antigen Antibodies, Monoclonal - chemistry Antibodies, Monoclonal - immunology Antibodies, Monoclonal - metabolism Antigens, CD - immunology Antigens, CD - metabolism Biological markers Biomarkers - analysis Biomarkers - chemistry Care and treatment Cell Line, Tumor Cell lines Cell Membrane - metabolism Cell Nucleus - metabolism Cytoplasm - metabolism Cytoplasmic Vesicles - metabolism Diagnosis Endocytosis - immunology Endoglin Flow Cytometry Forkhead Box Protein M1 Forkhead Transcription Factors - chemistry Forkhead Transcription Factors - metabolism Glioblastoma - diagnosis Glioblastoma - metabolism Glioblastoma - ultrastructure Glioblastoma multiforme Glycoproteins - immunology Glycoproteins - metabolism Health aspects Humans Hyaluronan Receptors - immunology Hyaluronan Receptors - metabolism Immunophenotyping Integrin beta1 - immunology Integrin beta1 - metabolism Magnetite Nanoparticles - chemistry Microscopy, Electron, Transmission Monoclonal antibodies Nanomedicine - methods Nanoparticles - chemistry Peptides - immunology Peptides - metabolism Physiological aspects Prognosis Quantum Dots Receptors, Cell Surface - immunology Receptors, Cell Surface - metabolism Staining and Labeling - methods Tumor Cells, Cultured
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Beschreibung
Zusammenfassung:	Despite recent advances, patients with malignant brain tumors still have a poor prognosis. Glioblastoma (WHO grade 4 astrocytoma), the most malignant brain tumor, represents 50% of all astrocytomas, with a median survival rate of
ISSN:	1084-9785 1557-8852
DOI:	10.1089/cbr.2009.0697