Effect of Intrasplenic Injections of Alloxan in the Rat.

Summary The present observations indicate that alloxan is just as effective as a diabetogenic agent when given intrasplenically as when given subcutaneously. Similar amounts of alloxan given intraperitoneally result in many instances in a milder diabetes. It appears that alloxan is not inactivated s...

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Veröffentlicht in:Experimental biology and medicine (Maywood, N.J.) N.J.), 1948-01, Vol.67 (1), p.57-58
1. Verfasser: Janes, Ralph G.
Format: Artikel
Sprache:eng
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Zusammenfassung:Summary The present observations indicate that alloxan is just as effective as a diabetogenic agent when given intrasplenically as when given subcutaneously. Similar amounts of alloxan given intraperitoneally result in many instances in a milder diabetes. It appears that alloxan is not inactivated specifically in the liver.
ISSN:0037-9727
1535-3702
1535-3699
DOI:10.3181/00379727-67-16202