A histological evaluation of the effect of hydroxyapatite coating on interfacial response

The effect of hydroxyapatite (HA) coating on cortical bone apposition around press-fit inserted implants and implants surrounded by a gap was investigated. Uncoated and HA-coated titanium implants were inserted in burr holes with three different diameters in the tibia of rabbits. Implantation time was four months. The histological evaluation demonstrated that after four months implantation the interfacial bone reaction appeared to be identical for HA-coated and non-coated implants with various degrees of surgical fit. Although after four months the interface showed the same response, there still might be an initial advantage of the HA-interface with bony tissue.