New Antifungal Terpenoid Glycosides from Alibertia edulis (Rubiaceae)

Phytochemical investigation from the stems of Alibertia edulis led to the isolation and identification of a new iridoid 6β‐hydroxy‐7‐epigardoside methyl ester (1) and a new saponin 3β‐O‐[α‐L‐rhamnopyranosyl‐(1→2)‐O‐β‐D‐glucopyranosyl‐(1→2)‐O‐β‐D‐glucopyranosyl]‐28‐O‐β‐D‐glucopyranoside pomolate (2), along with three known compounds, shanzhiside methyl ester (3), ixoside (4), and 3,4,5‐trimethoxyphenyl 1‐O‐β‐D‐apiofuranosyl‐(1→6)‐O‐β‐D‐glucopyranoside (5). The structures of 1 and 2 were established on the basis of their spectroscopic data. Iridoid 1 and saponin 2 exhibited moderate inhibitory activities against Candida albicans and C. krusei in a dilution assay.