25-Hydroxyvitamin D, dementia, and cerebrovascular pathology in elders receiving home services

Vitamin D deficiency has potential adverse effects on neurocognitive health and subcortical function. However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD). Cross-sectional investigation of 25-hydroxyvitamin...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Neurology 2010-01, Vol.74 (1), p.18-26
Hauptverfasser:	Buell, J S, Dawson-Hughes, B, Scott, T M, Weiner, D E, Dallal, G E, Qui, W Q, Bergethon, P, Rosenberg, I H, Folstein, M F, Patz, S, Bhadelia, R A, Tucker, K L
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Alzheimer Disease - etiology Body Mass Index Confidence Intervals Cross-Sectional Studies Dementia - classification Dementia - etiology Female Humans Logistic Models Magnetic Resonance Imaging - methods Male Neurologic Examination - methods Odds Ratio Phlebotomy - methods Retrospective Studies Risk Factors Stroke - etiology Temporal Lobe - pathology Vitamin D - analogs & derivatives Vitamin D - blood Vitamin D Deficiency - complications
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Vitamin D deficiency has potential adverse effects on neurocognitive health and subcortical function. However, no studies have examined the association between vitamin D status, dementia, and cranial MRI indicators of cerebrovascular disease (CVD). Cross-sectional investigation of 25-hydroxyvitamin D [25(OH)D], dementia, and MRI measures of CVD in elders receiving home care (aged 65-99 years) from 2003 to 2007. Among 318 participants, the mean age was 73.5 +/- 8.1 years, 231 (72.6%) were women, and 109 (34.3%) were black. 25(OH)D concentrations were deficient (
ISSN:	0028-3878 1526-632X
DOI:	10.1212/WNL.0b013e3181beecb7