Review of Biologic Therapies

Review of Biologic Therapies

The emergence of biologic therapy as treatment for autoimmune and inflammatory diseases is rapidly changing the face of medicine. From fusion proteins to monoclonal antibodies, biologic therapies encompass a variety of agents that target distinct pathways involved in autoimmunity and inflammation. I...

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Veröffentlicht in:Neuro-ophthalmology (Amsterdam : Aeolus Press. 1980) 2009-12, Vol.33 (6), p.286-299
Hauptverfasser: Tehrani, Rodney, Ostrowski, Rochella A, Hariman, Richard, Jay, Walter M.
Format: Artikel
Sprache:eng
Schlagworte:
abatacept
adalimumab
anakinra
certolizumab
Etanercept
golimumab
infliximab
rituximab
tocilizumab
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Zusammenfassung:The emergence of biologic therapy as treatment for autoimmune and inflammatory diseases is rapidly changing the face of medicine. From fusion proteins to monoclonal antibodies, biologic therapies encompass a variety of agents that target distinct pathways involved in autoimmunity and inflammation. In this review, a survey of available and emerging biologic therapies detailing their current indications, mechanism of action, dosing, side effects, and recommended drug monitoring will be summarized so as to aid clinicians in making treatment decisions regarding their usage.
ISSN:0165-8107
1744-506X
DOI:10.3109/01658100903360064