Induced Latent Infection and Resultant Active Immunity to M M Mouse Encephalomyelitis Virus in Mice Suckled by Immune Foster Mothers

Specific protective antibodies against M M strain of mouse encephalomyelitis virus, transmitted passively from immune female mice through milk to adopted nonimmune sucklings, protect against otherwise lethal doses of virus. The immunity is essentially complete during the first month of life; it ends...

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Veröffentlicht in:The Journal of infectious diseases 1949-11, Vol.85 (3), p.259-262
Hauptverfasser: Gordon, John E., Curley, Francis J.
Format: Artikel
Sprache:eng
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Zusammenfassung:Specific protective antibodies against M M strain of mouse encephalomyelitis virus, transmitted passively from immune female mice through milk to adopted nonimmune sucklings, protect against otherwise lethal doses of virus. The immunity is essentially complete during the first month of life; it ends in the third month. The balance between infection and immunity brought about by administration of unmodified virus during the second month results in latent infection and active immunization.
ISSN:0022-1899
DOI:10.1093/infdis/85.3.259