Neuronal localisation of immunoreactive enkephalin and β-endorphin in the earthworm

Neuronal localisation of immunoreactive enkephalin and β-endorphin in the earthworm

SINCE the report by Simantov et al. 1 invertebrates have been thought to lack endogenous opiates and opiate receptors. As we have previously observed peptidergic neurones containing immunoreactive pancreatic polypeptide or vasoactive intestinal peptide in the earthworm 2 , we decided to search for,...

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Veröffentlicht in:Nature (London) 1979-06, Vol.279 (5716), p.805-806
Hauptverfasser: ALUMETS, J., HÅKANSON, R., SUNDLER, F., THORELL, J.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Endorphins - analysis
Enkephalins - analysis
Fluorescent Antibody Technique
Humanities and Social Sciences
letter
multidisciplinary
Neurons - analysis
Oligochaeta - analysis
Receptors, Opioid
Science
Science (multidisciplinary)
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Zusammenfassung:SINCE the report by Simantov et al. 1 invertebrates have been thought to lack endogenous opiates and opiate receptors. As we have previously observed peptidergic neurones containing immunoreactive pancreatic polypeptide or vasoactive intestinal peptide in the earthworm 2 , we decided to search for, and report here our finding of, nerves storing immunoreactive enkephalin or β -endorphin in this species.
ISSN:0028-0836
1476-4687
DOI:10.1038/279805a0