Effects of estrogen on gene expression in rooster liver

Effects of estrogen on gene expression in rooster liver

The effects of estrogen on RNA sequence complexity and sequence frequency were studied in rooster liver. Both control and estrogen-treated liver contained total RNA sequence diversity of approximately 4.2 × 10 7 nucleotides. Two components were found in the reaction of chicken liver or brain RNA wit...

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Veröffentlicht in:Biochemical and biophysical research communications 1979-02, Vol.86 (3), p.545-551
Hauptverfasser: Grouse, John M., Grouse, Lawrence D.
Format: Artikel
Sprache:eng
Schlagworte:
Animals
Base Sequence
Estrogens - pharmacology
Fibroblasts - metabolism
Liver - drug effects
Liver - metabolism
Male
Nucleic Acid Hybridization
RNA - biosynthesis
Transcription, Genetic - drug effects
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Zusammenfassung:The effects of estrogen on RNA sequence complexity and sequence frequency were studied in rooster liver. Both control and estrogen-treated liver contained total RNA sequence diversity of approximately 4.2 × 10 7 nucleotides. Two components were found in the reaction of chicken liver or brain RNA with unique DNA: RNA species present at high concentration and RNA species about 100-fold less abundant. Approximately 7 × 10 6 nucleotides of RNA sequence complexity were present at high concentration in estrogen-treated liver but not at high concentration in control liver.
ISSN:0006-291X
1090-2104
DOI:10.1016/0006-291X(79)91748-0