In vitro studies on microphage functions in chronic pyoderma vegetans

The function of microphages has been studied in two patients with chronic pyoderma vegetans by in vitro determination of phagocytosis as well as chemotaxis. The results showed a striking decrease in the chemotactic activity of the neutrophil granulocytes, a reduced phagocytosis of Candida albicans a...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Archives of Dermatological Research 1978-01, Vol.263 (1), p.97-104
Hauptverfasser:	Djawari, D, Hornstein, O P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Candida albicans - immunology Chemotaxis, Leukocyte Chronic Disease Humans Male NADH Tetrazolium Reductase - metabolism Neutrophils - enzymology Nitroblue Tetrazolium Phagocytes - physiology Phagocytosis Pyoderma - immunology Pyoderma - microbiology Pyoderma - pathology Staphylococcus aureus - immunology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	The function of microphages has been studied in two patients with chronic pyoderma vegetans by in vitro determination of phagocytosis as well as chemotaxis. The results showed a striking decrease in the chemotactic activity of the neutrophil granulocytes, a reduced phagocytosis of Candida albicans and Staphylococcus aureus, and a weakness of the intracellular killing of these microorganisms. However, the NADH-dependent oxidase activity appeared to be intact. No defect was found in the specific cellular or humoral immune system in either patient.
ISSN:	0340-3696 1432-069X
DOI:	10.1007/BF00446859