Evolutionary trace of human odorant receptors of chromosome 17

Studies on the odorant receptor cluster located on human chromosome 17, which contains 18 odorant receptor genes, are presented. After an extended search for orthologues of those odorant receptor genes in chimpanzee, rat and mouse genomes, comparisons subject to genomic location, similarities and fu...

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Veröffentlicht in:	Flavour and fragrance journal 2009-07, Vol.24 (4), p.192-197
Hauptverfasser:	Knape, Kirsten, Beyer, Anton, Stary, Anna, Buchbauer, Gerhard, Wolschann, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical, structural and metabolic biochemistry Biological and medical sciences comparative genomics Dna, deoxyribonucleoproteins Fundamental and applied biological sciences. Psychology helional recognition human chromosome 17 Nucleic acids odorant receptor Pan troglodytes
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Beschreibung
Zusammenfassung:	Studies on the odorant receptor cluster located on human chromosome 17, which contains 18 odorant receptor genes, are presented. After an extended search for orthologues of those odorant receptor genes in chimpanzee, rat and mouse genomes, comparisons subject to genomic location, similarities and function were made. Different ways of evolutionary propagation can be observed. This leads to conversion into pseudogenes, but also duplication of some genes occurs. Copyright © 2009 John Wiley & Sons, Ltd.
ISSN:	0882-5734 1099-1026
DOI:	10.1002/ffj.1933