Differential Requirement for H2AX and 53BP1 in Organismal Development and Genome Maintenance in the Absence of Poly(ADP)ribosyl Polymerase 1

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Veröffentlicht in:	Molecular and Cellular Biology 2010-05, Vol.30 (10), p.2341-2352
Hauptverfasser:	Orsburn, Benjamin, Escudero, Beatriz, Prakash, Mansi, Gesheva, Silvia, Liu, Guosheng, Huso, David L., Franco, Sonia
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals B-Lymphocytes - cytology B-Lymphocytes - metabolism Chromosomal Proteins, Non-Histone DNA - drug effects DNA - genetics DNA - metabolism DNA - radiation effects DNA Breaks, Double-Stranded - drug effects DNA Breaks, Double-Stranded - radiation effects DNA Repair DNA-Activated Protein Kinase - genetics DNA-Activated Protein Kinase - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Female Genome Genomic Instability Histones - genetics Histones - metabolism Humans Hydroxyurea - pharmacology In Situ Hybridization, Fluorescence Intracellular Signaling Peptides and Proteins - genetics Intracellular Signaling Peptides and Proteins - metabolism Male Mice Mice, Knockout Mitomycin - pharmacology Nuclear Proteins - genetics Nuclear Proteins - metabolism Nucleic Acid Synthesis Inhibitors - pharmacology Phenotype Poly (ADP-Ribose) Polymerase-1 Poly(ADP-ribose) Polymerases - genetics Poly(ADP-ribose) Polymerases - metabolism Rad51 Recombinase - genetics Rad51 Recombinase - metabolism Radiation, Ionizing Sister Chromatid Exchange Tumor Suppressor p53-Binding Protein 1
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Zusammenfassung:	Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue Spotlights in the Current Issue MCB About MCB Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy MCB RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0270-7306 Online ISSN: 1098-5549 Copyright © 2014 by the American Society for Microbiology. For an alternate route to MCB .asm.org, visit: MCB
ISSN:	0270-7306 1098-5549 1098-5549
DOI:	10.1128/MCB.00091-10