Emerging cystic fibrosis pathogens: incidence and antimicrobial resistance

We examined the frequency of isolation and the antimicrobial resistance of Burkholderia cepacia complex, Stenotrophomonas maltophilia and Achromobacter xylosoxidans in cystic fibrosis patients from 2000 to 2004. Strains susceptibility to tobramycin, piperacillin/tazobactam, imipenem, gentamicin, cip...

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Veröffentlicht in:	The New microbiologica 2007-01, Vol.30 (1), p.59-62
Hauptverfasser:	Magni, Annarita, Giordano, Alessandra, Mancini, Carlo, Pecoraro, Claudia, Varesi, Paola, Quattrucci, Serena, Trancassini, Maria
Format:	Artikel
Sprache:	eng
Schlagworte:	Achromobacter - drug effects Adolescent Anti-Bacterial Agents - pharmacology Burkholderia cepacia complex - drug effects Cystic Fibrosis - epidemiology Cystic Fibrosis - microbiology Drug Resistance, Bacterial Gram-Negative Bacterial Infections - epidemiology Gram-Negative Bacterial Infections - microbiology Humans Incidence Italy - epidemiology Microbial Sensitivity Tests Xanthomonadaceae - drug effects
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Zusammenfassung:	We examined the frequency of isolation and the antimicrobial resistance of Burkholderia cepacia complex, Stenotrophomonas maltophilia and Achromobacter xylosoxidans in cystic fibrosis patients from 2000 to 2004. Strains susceptibility to tobramycin, piperacillin/tazobactam, imipenem, gentamicin, ciprofloxacin and ceftazidime was determined by disc diffusion assay. B. cepacia complex showed a very high resistance also to ciprofloxacin reaching 100% in 2004. S. maltophilia and A. xvylosoxidans showed high rates of antimicrobial resistance both aminoglycoside and ciprofloxacin. It is very important to monitor the percentage of isolation of these species over time to verify strains resistance to antibiotics and also to test new combinations of antimicrobial agents.
ISSN:	1121-7138