Studies of left-handed Z-DNA. Characteristics of Raman spectra of d(GpCpGpCpGpC)

Studies of laser Raman spectra of synthesized DNA fragment, d(GpCpGpCpGpC), were performed. The similarities and differences between the characteristic spectra of the aligomer and those of its structural components, 5-dGMP and 5'-dCMP, were discussed. The information obtained on the characteris...

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Veröffentlicht in:Chinese Journal of Lasers B 1993-01, Vol.B2 (2), p.181-188
Hauptverfasser: Huang, Ruduo, Huang, Demin, Wang, Zhenhai, Dai, Yanzhi, Cui, Yiben, Gong, Lisan, Liu, Sonhao, Ling, Zhenho, Tang, Jinyan
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Sprache:eng
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Zusammenfassung:Studies of laser Raman spectra of synthesized DNA fragment, d(GpCpGpCpGpC), were performed. The similarities and differences between the characteristic spectra of the aligomer and those of its structural components, 5-dGMP and 5'-dCMP, were discussed. The information obtained on the characteristic of Raman spectrum susceptible to B-2 conformation transition of aligomer is helpful in further investigation of the biology of left-handed DNA.
ISSN:1004-2822