Candida spp. in vitro susceptibility profile to four antifungal agents. Resistance surveillance study in Venezuelan strains

The aim of this study was to determine in vitro susceptibility profiles of Venezuelan strains of Candida spp. to four antifungal agents. One hundred and forty five (145) isolates were recovered during a 1-year period (June 2006 to June 2007) from clinical specimens of patients with severe Candida sp...

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Veröffentlicht in:	Medical mycology (Oxford) 2009-01, Vol.47 (2), p.137-143
Hauptverfasser:	Panizo, María Mercedes, Reviákina, Vera, Dolande, Maribel, Selgrad, Sofía
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Amphotericin B - pharmacology Antifungal Agents - pharmacology Azoles - pharmacology Candida - classification Candida - drug effects Candida - isolation & purification Candida albicans Candida albicans - drug effects Candida albicans - isolation & purification Candidiasis - epidemiology Candidiasis - microbiology Child Child, Preschool Drug Resistance, Fungal Female Fluconazole - pharmacology Humans Infant Itraconazole - pharmacology Male Microbial Sensitivity Tests Middle Aged Population Surveillance - methods Pyrimidines - pharmacology Triazoles - pharmacology Venezuela - epidemiology Voriconazole Young Adult
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Zusammenfassung:	The aim of this study was to determine in vitro susceptibility profiles of Venezuelan strains of Candida spp. to four antifungal agents. One hundred and forty five (145) isolates were recovered during a 1-year period (June 2006 to June 2007) from clinical specimens of patients with severe Candida spp. infections in 15 hospitals. In vitro susceptibilities to amphotericin B, fluconazole, itraconazole and voriconazole were determined by modified Etest®. Non Candida albicans Candida spp. were the most frequently isolated yeasts (72.4%) in comparison with C. albicans (27.6%). Candida spp. strains showed MIC ranges between
ISSN:	1369-3786 1460-2709
DOI:	10.1080/13693780802144339