The Nuclear Receptor Superfamily and Drug Discovery
Targeting the nuclear receptors: The ligand‐binding domain of the glucocorticoid receptor (ribbon) bound with the ligand, dexamethasone (space‐filling) is just one of the many pictures that are becoming clearer in the field of nuclear receptor (NR) research. Recent developments in drug discovery sho...
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| Veröffentlicht in: | ChemMedChem 2006-05, Vol.1 (5), p.504-523 |
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| container_title | ChemMedChem |
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| creator | Moore, John T. Collins, Jon L. Pearce, Kenneth H. |
| description | Targeting the nuclear receptors: The ligand‐binding domain of the glucocorticoid receptor (ribbon) bound with the ligand, dexamethasone (space‐filling) is just one of the many pictures that are becoming clearer in the field of nuclear receptor (NR) research. Recent developments in drug discovery show great promise for the treatment of many NR‐related diseases. |
| doi_str_mv | 10.1002/cmdc.200600006 |
| format | Article |
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| fulltext | fulltext |
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| ispartof | ChemMedChem, 2006-05, Vol.1 (5), p.504-523 |
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| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Drug Design gene expression inhibitors Ligands medicinal chemistry Models, Molecular receptors Receptors, Cytoplasmic and Nuclear - physiology |
| title | The Nuclear Receptor Superfamily and Drug Discovery |
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